Transgenic Livestock - Review -
نویسندگان
چکیده
منابع مشابه
Transgenic livestock: premises and promises.
Microinjection of DNA constructs into pronuclei of zygotes has been the method of choice for the generation of transgenic livestock. However, this procedure is characterized by low efficiency (1-4% transgenic offspring), random integration and variable expression of the transgene as well as a considerable proportion of mosaicism. Furthermore, it is extremely time consuming and costly. As a cons...
متن کاملResource requirements for transgenic livestock research.
Transgenic research usually involves a large investment in carrying out a series of low-efficiency steps to produce a few transgenic founder animals, and then characterizing a transgenic line of animals derived from each founder. There is considerable variation in phenotype among transgenic lines made with the same DNA construct. In the case of livestock species, to produce one founder animal t...
متن کاملTransgenic livestock for agriculture and biomedical applications
The classical definition of a genetically engineered or “transgenic” animal would be “those animals modified by recombinant DNA (rDNA) techniques” according to the U.S. Food and Drug Administration (United States Food and Drug Administration, Guidance #187, 2009). Thus, the introduction or deletion of any gene by using recombinant DNA would fall into this category. Since the first reports of st...
متن کاملLivestock metabolomics and the livestock metabolome: A systematic review
Metabolomics uses advanced analytical chemistry techniques to comprehensively measure large numbers of small molecule metabolites in cells, tissues and biofluids. The ability to rapidly detect and quantify hundreds or even thousands of metabolites within a single sample is helping scientists paint a far more complete picture of system-wide metabolism and biology. Metabolomics is also allowing r...
متن کاملGeneration of transgenic livestock by somatic cell nuclear transfer
The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have either been inefficient or not available in all animals. More recently, somatic cell nuclear transfer has provided a method to create transgenic a...
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ژورنال
عنوان ژورنال: Asian-Australasian Journal of Animal Sciences
سال: 1994
ISSN: 1011-2367,1976-5517
DOI: 10.5713/ajas.1994.1